Gravitational Microlensing by Neutron Stars and Radio Pulsars: Event Rates, Timescale Distributions, and Mass Measurements

We investigate properties of Galactic microlensing events in which a stellar object is lensed by a neutron star. For an all-sky photometric microlensing survey, we determine the number of lensing events caused by $\sim10^{5}$ potentially-observable radio pulsars to be $\sim0.2\ \rm{yr^{-1}}$ for $10^{10}$ background stellar sources. We expect a few detectable events per year for the same number of background sources from an astrometric microlensing survey. We show that such a study could lead to precise measurements of radio pulsar masses. For instance, if a pulsar distance could be constrained through radio observations, then its mass would be determined with a precision of $\sim10\%$. We also investigate the time-scale distributions for neutron star events, finding that they are much shorter than had been previously thought. For photometric events towards the Galactic centre that last $\sim15$ days, around $7\%$ will have a neutron star lens. This fraction drops rapidly for longer time-scales. Away from the bulge region we find that neutron stars will contribute $\sim40\%$ of the events that last less than $\sim10$ days. These results are in contrast to earlier work which found that the maximum fraction of neutron star events would occur on time-scales of hundreds of days.Comment: 10 pages, accepted for publication in ApJ. v2 updated to reflect change of title in proof stag

Detect Related Bugs from Source Code Using Bug Information

Open source projects often maintain open bug repositories during development and maintenance, and the reporters often point out straightly or implicitly the reasons why bugs occur when they submit them. The comments about a bug are very valuable for developers to locate and fix the bug. Meanwhile, it is very common in large software for programmers to override or overload some methods according to the same logic. If one method causes a bug, it is obvious that other overridden or overloaded methods maybe cause related or similar bugs. In this paper, we propose and implement a tool Rebug- Detector, which detects related bugs using bug information and code features. Firstly, it extracts bug features from bug information in bug repositories; secondly, it locates bug methods from source code, and then extracts code features of bug methods; thirdly, it calculates similarities between each overridden or overloaded method and bug methods; lastly, it determines which method maybe causes potential related or similar bugs. We evaluate Rebug-Detector on an open source project: Apache Lucene-Java. Our tool totally detects 61 related bugs, including 21 real bugs and 10 suspected bugs, and it costs us about 15.5 minutes. The results show that bug features and code features extracted by our tool are useful to find real bugs in existing projects.Comment: 10 pages, 5 figures, 4 tables conference; 2010 IEEE 34th Annual Computer Software and Applications Conferenc

3D Interacting Hand Pose Estimation by Hand De-occlusion and Removal

Estimating 3D interacting hand pose from a single RGB image is essential for understanding human actions. Unlike most previous works that directly predict the 3D poses of two interacting hands simultaneously, we propose to decompose the challenging interacting hand pose estimation task and estimate the pose of each hand separately. In this way, it is straightforward to take advantage of the latest research progress on the single-hand pose estimation system. However, hand pose estimation in interacting scenarios is very challenging, due to (1) severe hand-hand occlusion and (2) ambiguity caused by the homogeneous appearance of hands. To tackle these two challenges, we propose a novel Hand De-occlusion and Removal (HDR) framework to perform hand de-occlusion and distractor removal. We also propose the first large-scale synthetic amodal hand dataset, termed Amodal InterHand Dataset (AIH), to facilitate model training and promote the development of the related research. Experiments show that the proposed method significantly outperforms previous state-of-the-art interacting hand pose estimation approaches. Codes and data are available at https://github.com/MengHao666/HDR.Comment: ECCV202

Observation of spin-tensor induced topological phase transitions of triply degenerate points with a trapped ion

Triply degenerate points (TDPs), which correspond to new types of topological semimetals, can support novel quasiparticles possessing effective integer spins while preserving Fermi statistics. Here by mapping the momentum space to the parameter space of a three-level system in a trapped ion, we experimentally explore the transitions between different types of TDPs driven by spin-tensor--momentum couplings. We observe the phase transitions between TDPs with different topological charges by measuring the Berry flux on a loop surrounding the gap-closing lines, and the jump of the Berry flux gives the jump of the topological charge (up to a $2\pi$ factor) across the transitions. For the Berry flux measurement, we employ a new method by examining the geometric rotations of both spin vectors and tensors, which lead to a generalized solid angle equal to the Berry flux. The controllability of multi-level ion offers a versatile platform to study high-spin physics and our work paves the way to explore novel topological phenomena therein.Comment: 9 pages, 10 figure

Dual Supramolecular Nanoparticle Vectors Enable CRISPR/Cas9-Mediated Knockin of Retinoschisin 1 Gene-A Potential Nonviral Therapeutic Solution for X-Linked Juvenile Retinoschisis.

The homology-independent targeted integration (HITI) strategy enables effective CRISPR/Cas9-mediated knockin of therapeutic genes in nondividing cells in vivo, promising general therapeutic solutions for treating genetic diseases like X-linked juvenile retinoschisis. Herein, supramolecular nanoparticle (SMNP) vectors are used for codelivery of two DNA plasmids-CRISPR-Cas9 genome-editing system and a therapeutic gene, Retinoschisin 1 (RS1)-enabling clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9 (CRISPR/Cas9) knockin of the RS1 gene with HITI. Through small-scale combinatorial screenings, two SMNP vectors, with Cas9 and single guide RNA (sgRNA)-plasmid in one and Donor-RS1 and green fluorescent protein (GFP)-plasmid in the other, with optimal delivery performances are identified. These SMNP vectors are then employed for CRISPR/Cas9 knockin of RS1/GFP genes into the mouse Rosa26 safe-harbor site in vitro and in vivo. The in vivo study involves intravitreally injecting the two SMNP vectors into the mouse eyes, followed by repeated ocular imaging by fundus camera and optical coherence tomography, and pathological and molecular analyses of the harvested retina tissues. Mice ocular organs retain their anatomical integrity, a single-copy 3.0-kb RS1/GFP gene is precisely integrated into the Rosa26 site in the retinas, and the integrated RS1/GFP gene is expressed in the retinas, demonstrating CRISPR/Cas9 knockin of RS1/GFP gene